Tuesday, December 15, 2009

The Infamous "K-Hole"

The Infamous "K-Hole": Recreational use of ketamine has skyrocketed in recent years. Like most anesthetics, its recreational value went undiscovered until decades after it was first synthesized. In the early 1960s, scientists began to develop anesthetics with reduced psychoactive side effects. Ketamine was one of the primary drugs to originate from this development process. And as such, it underwent immediate testing in both animals and humans. Essentially, the drug acts on the central nervous system by inhibiting neuron transmission, which impedes the brain's ability to access memory. This effect made the drug a hit among wounded soldiers in the Vietnam War, as their brains were unable to process the pain "memory." Today, ketamine is primarily used in veterinary medicine because it still possesses a variety of hallucinogenic effects, many of which are similar to PCP. As a result, the drug is also used in the "rave" scene, where ecstasy (MDMA) and other amphetamines are popular. Where the term "K-Hole" becomes relevant is when a ketamine user consumes a particularly high dose. The net effect of such an act will cause a kind of paralysis where the user experiences a psychedelic detachment from the body.

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